OSTEOTROPIC BIOMATERIALS, METHODS OF USE THEREOF AND IMPLANT SYSTEMS INCORPORATING THE SAME

摘要

An osteotropic compound of the Formula P-L-S is described, wherein P is a biodegradable polymer such as a polyester polymer, L is a linking group such as a covalent bond or carbonyl, and S is an osteotropic group such as a statin. Scaffold bodies formed from such compounds are described, along with such bodies containing bone cells such as bone marrow cells and methods of use thereof.