Inhibitors for suppressing the activity of proteins displaying CIITA activity, methods for their identification and pharmaceutical compositions

摘要

The invention relates to inhibitors suppressing the activity of transacting proteins which are essential for the general control of vertebrate MHC class II gene expression and methods for identifying the same. The invention additionally relates to pharmaceutical compositions containing said inhibitors, preferably for the treatment of diseases which are associated with an aberrant expression of MHC class II genes.