OUTER MEMBRANE ASSOCIATED POLYPEPTIDES

摘要

The invention provides methods for the localization and recovery of outer membrane associated polypeptides that are useful for the immunization (both active and passive) of mammals, poultry and man for protection against disease and infection caused by bacteria, fungi, and/or protozoans. These are separated from contaminating endotoxins and target ligands. Purified and/or synthetic peptides can be used in immunization strategies for the broad or species-specific protection against bacteria, fungi, or protozoans. The invention further provides methods for diagnosing bacteria, fungi, or protozoans.