| 摘要 |
A method and system for use in treating a patient receiving any drug to optimize therapy and to prevent an adverse drug response. This system employs surrogate markers or indicators, including blood levels of drug, to determine the next required dose for a patient. Virtually any indicator can be used as the surrogate marker. Surrogate markers could include any measure of the effectiveness of a drug's action. Given the effectiveness of the drug's action, relative to the surrogate markers, a change in drug dose is calculated by the system wich uses a stochastic loop mechanism. Conversely, by employing this system, one could determine the expected result of a drug dose change based on the surrogate markers. |
