发明名称 |
Master bone formation transcription factor: compositions and methods of use |
摘要 |
A novel gene expressed selectively by osteoblast lines is provided. Expression of the gene is highly restricted to cells of osteoblast lineage, including precursor cells. Also provided is a method for promoting bone formation by providing agents that bind to the novel gene within osteoblast cells to stimulate bone formation.
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申请公布号 |
US2002156031(A1) |
申请公布日期 |
2002.10.24 |
申请号 |
US20000734329 |
申请日期 |
2000.11.30 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
DE CROMBRUGGHE BENOIT;NAKASHIMA KAZUHISA;ZHOU XIN |
分类号 |
G01N33/50;A61K35/76;A61K38/00;A61K48/00;A61P19/10;A61P43/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12Q1/02;C12Q1/68;G01N33/15;(IPC1-7):A61K48/00;C07H21/04;C12N9/64;C12N5/08 |
主分类号 |
G01N33/50 |
代理机构 |
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地址 |
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