发明名称 Master bone formation transcription factor: compositions and methods of use
摘要 A novel gene expressed selectively by osteoblast lines is provided. Expression of the gene is highly restricted to cells of osteoblast lineage, including precursor cells. Also provided is a method for promoting bone formation by providing agents that bind to the novel gene within osteoblast cells to stimulate bone formation.
申请公布号 US2002156031(A1) 申请公布日期 2002.10.24
申请号 US20000734329 申请日期 2000.11.30
申请人 BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 发明人 DE CROMBRUGGHE BENOIT;NAKASHIMA KAZUHISA;ZHOU XIN
分类号 G01N33/50;A61K35/76;A61K38/00;A61K48/00;A61P19/10;A61P43/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12Q1/02;C12Q1/68;G01N33/15;(IPC1-7):A61K48/00;C07H21/04;C12N9/64;C12N5/08 主分类号 G01N33/50
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