发明名称 |
Reduction of antioxidant enzyme levels in tumor cells using antisense oligonucleotides |
摘要 |
The present invention provides an antisense oligonucleotide that specifically binds to an antioxidant enzyme start codon so as to inhibit the level of antioxidant enzymes in a cell. The present invention further provides methods of treating an antioxidant enzyme malfunction disorder in a mammal by reducing antioxidant enzyme levels in a cell with the administration of the antisense oligonucleotide.
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申请公布号 |
US2002156040(A1) |
申请公布日期 |
2002.10.24 |
申请号 |
US20010993333 |
申请日期 |
2001.11.14 |
申请人 |
OBERLEY LARRY WAYNE;WEYDERT CHRISTINE J.;SMITH BENJAMIN BARNES |
发明人 |
OBERLEY LARRY WAYNE;WEYDERT CHRISTINE J.;SMITH BENJAMIN BARNES |
分类号 |
A61K38/00;A61P9/00;A61P19/02;A61P25/28;A61P35/00;C12N15/113;(IPC1-7):A61K48/00;C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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