发明名称 PROTEIN PRENYL TRANSFERASE INHIBITORS IN THE TREATMENT OF NEUROINFLAMMATORY DISEASE
摘要 A protein prenyl transferase inhibitor is used in the treatment of neuroinflammatory disease such as MS, uveitis, alzheimers or neuroAIDS. The inhibitor may be a combination of a farnesyl transferase inhibitor and a geranylgeranyl transferase inhibitor. Preferably, FTI-277 and/or GGTI-298 is employed.
申请公布号 WO0240015(A8) 申请公布日期 2002.10.24
申请号 WO2001GB04291 申请日期 2001.09.26
申请人 INSTITUTE OF OPHTHALMOLOGY;ADAMSON, PETER;GREENWOOD, JOHN 发明人 ADAMSON, PETER;GREENWOOD, JOHN
分类号 A61K45/00;A61K31/00;A61K31/198;A61K45/06;A61P25/00;A61P25/28;A61P43/00;(IPC1-7):A61K31/24 主分类号 A61K45/00
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