IN VITRO TEST SYSTEM FOR GAMMA SECRETASE FROM ENRICHED MEMBRANES.

摘要

The invention relates to a method for identifying specific ggr; secretase inhibitors which can be used for treating neuro degenerative diseases, in particular to a method which can be carried out in vitro. The invention also relates to a test kit which can be used for said method, in addition to the use of this test kit or method to identify substances which specifically inhibit ggr; secretase. A further embodiment relates to the use of these substances to produce a medicament for treating neuro degenerative diseases and to pharmaceutical formulations which contain said substances.