HETEROALKYLAMINO SUBSTITUTED BICYCLIC NITROGEN HETEROCYCLES AS INHIBITORS OF P38 PROTEIN KINASE.

摘要

The invention provides compounds represented by formula (I) in which R1, R2, R3, R4, and n are as defined in the application; and individual isomers, racemic or non racemic mixtures of isomers, and pharmaceutically acceptable salts thereof. The compounds are p38 inhibitors and may be used in the treatment of arthritis, Crohn s disease, irritable bowel syndrome, adult respiratory distress syndrome, chronic obstructive pulmonary disease, osteoporosis, or Alzheimer s disease.