Medicament for the alleviation or treatment of symptom derived from the ischemic disease and compound useful thereof

摘要

A medicine having the following basic structure, for the alleviation or treatment of symptoms derived from ischemic diseases and seizures, epilepsy, and migraine, having a powerful action in suppressing cytotoxic Ca2+ overload and free from side-effects:wherein Z=C, CH, or N, X=O or CH2, E and Y=H, OH, a halogen, alkoxy, alkyl, or a halogen-substituted alkyl.