PHARMACEUTICAL COMPOSITIONS COMPRISING DERIVATIVES OF HYDROXAMIC ACID

摘要

organic chemistry, pharmacy. SUBSTANCE: invention relates to a novel agent and pharmaceutical compositions based on thereof use for protection of mitochondrial genome and/or mitochondrions against damages or for treatment of diseases associated with these damages. An active component of the above-mentioned compositions is a derivative of hydroxamic acid of the formula (I) or its pharmaceutically acceptable acid-additive salt. Early this substance has been used for treatment of diabetes mellitus. Invention proposes an agent for treatment of myopathy and/or cardiomyopathy, or neurodegenerative diseases with a novel mechanism of action. EFFECT: new agent indicated above, valuable medicinal properties. 14 cl, 7 tbl, 7 test