发明名称 THERAPEUTIC METHOD FOR REDUCING ANGIOGENESIS
摘要 A method of controlling or treating an angiogenic dependent condition in a mammal, preferably in a human by administering an anti-angiogenic molecule such as an angiogenesis growth factor antagonist, and a chemotherapeutic agent in amounts and frequencies effective, in combination, to produce a regression or arrest of said condition while minimizing or preventing significant toxicity of the chemotherapeutic agent. Also a kit for controlling or treating an angiogenic dependent condition in a mammal, preferably in a human, comprising an anti-angiogenic molecule, such as an angiogenesis growth factor antagonist, and a chemotherapeutic agent in amounts effective, in combination, to produce a regression or arrest of said condition while minimizing or preventing significant toxicity of the chemotherapeutic agent.
申请公布号 WO0154723(A9) 申请公布日期 2002.10.17
申请号 WO2001US02839 申请日期 2001.01.29
申请人 SUNNYBROOK HEALTH SCIENCE CENTER;IMCLONE SYSTEMS INCORPORATED;KERBEL, ROBERT 发明人 KERBEL, ROBERT
分类号 A61K45/06;A61K39/395;A61P35/00;A61P37/02;A61P43/00;C07K16/28;G01N33/50;(IPC1-7):A61K39/395;A61K39/00;A61K39/38;G01N33/53 主分类号 A61K45/06
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