发明名称 METHOD OF KILLING TARGET CELLS IN HARVESTED CELL POPULATIONS WITH ONE OR MORE IMMUNO-TOXINS
摘要 A method for killing unwanted target cells in a cell population comprising nucleated cells harvested from peripheral blood, or CD-34+ or similar early progenitor cells selected from the above nucleated cells or from bone marrow aspirates, in which method the cell population is in vitro or in vivo exposed to two or more immunotoxins selectively killing the malignant cells, is described. Furthermore the invention relates to the mixture of immunotixins, the use of the mixture and a kit for performing the method.
申请公布号 US2002151689(A1) 申请公布日期 2002.10.17
申请号 US19980125751 申请日期 1998.10.30
申请人 OYSTEIN FODSTAD 发明人 FODSTAD OYSTEIN;KVALBEIM GUNNAR;WANG MENG;ENGEBRATEN OLAV;JUELL SIRI
分类号 A61K39/104;A61K31/00;A61K39/00;A61K39/385;A61K39/395;A61K47/48;A61P35/00;C12N5/00;C12N5/06;C12P21/08;(IPC1-7):C12P21/08;A61K39/40;A61K39/42;A61K39/44;C07K16/00 主分类号 A61K39/104
代理机构 代理人
主权项
地址