发明名称 |
METHOD OF KILLING TARGET CELLS IN HARVESTED CELL POPULATIONS WITH ONE OR MORE IMMUNO-TOXINS |
摘要 |
A method for killing unwanted target cells in a cell population comprising nucleated cells harvested from peripheral blood, or CD-34+ or similar early progenitor cells selected from the above nucleated cells or from bone marrow aspirates, in which method the cell population is in vitro or in vivo exposed to two or more immunotoxins selectively killing the malignant cells, is described. Furthermore the invention relates to the mixture of immunotixins, the use of the mixture and a kit for performing the method.
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申请公布号 |
US2002151689(A1) |
申请公布日期 |
2002.10.17 |
申请号 |
US19980125751 |
申请日期 |
1998.10.30 |
申请人 |
OYSTEIN FODSTAD |
发明人 |
FODSTAD OYSTEIN;KVALBEIM GUNNAR;WANG MENG;ENGEBRATEN OLAV;JUELL SIRI |
分类号 |
A61K39/104;A61K31/00;A61K39/00;A61K39/385;A61K39/395;A61K47/48;A61P35/00;C12N5/00;C12N5/06;C12P21/08;(IPC1-7):C12P21/08;A61K39/40;A61K39/42;A61K39/44;C07K16/00 |
主分类号 |
A61K39/104 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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