METHOD FOR REDUCING CELLULAR DAMAGE RESULTING FROM HYPOXIA/ISCHAEMIA-RELATED INFLAMMATION
摘要
The present invention provides means and methods for at least a partial prevention of cellular damage in disease resulting from hypoxia/ischaemia (H/I)-related inflammation, preferably due to occlusion of blood vessels. Administration of IFN type-I before, around or after the time of lifting of the ischaemia results in improved survival of cells downstream of the occluded blood vessel, presumable because the H/I-related inflammation is attenuated. Treatment results in less damage, better recovery and/or improved repair of the affected tissue.
申请公布号
WO02080953(A2)
申请公布日期
2002.10.17
申请号
WO2002NL00217
申请日期
2002.04.03
申请人
UNIVERSITAIR MEDISCH CENTRUM UTRECHT;UNIVERSITEIT UTRECHT;VELDHUIS, WOUTER, BERNARD;VAN DER MEIDE, PETRUS, HENDRIKUS;NICOLAY, KLAAS
发明人
VELDHUIS, WOUTER, BERNARD;VAN DER MEIDE, PETRUS, HENDRIKUS;NICOLAY, KLAAS