发明名称 AZOLYLCARBYNOL DERIVATIVES OF ARYL (OR HETEROARYL) FOR THE TREATMENT OF RESPIRATORY DISEASES
摘要 The invention relates to azolylcarbynol derivatives of aryl (or heteroaryl) of general formula (I), wherein Ar represents an optionally substituted phenyl or thyenyl radical; R1 represents a hydrogen atom or an inferior alkyl group; R2 represents a dialkylaminoalkyl or azaheterocyclilalkyl radical and Het represents a non-substituted azole or an azole optionally substituted by one or two substituents, and their physiologically acceptable salts. Said derivatives are useful as medicaments en human and/or veterinary therapy for the treatment of respiratory diseases, more particularly for the treatment of coughing, bronchitis, chronic obstructive lung diseases, allergic rhinitis and asthma.
申请公布号 WO02080908(A1) 申请公布日期 2002.10.17
申请号 WO2002ES00136 申请日期 2002.03.21
申请人 LABORATORIOS DEL DR. ESTEVE, S.A.;MERCE-VIDAL, RAMON;ANDALUZ-MATERO, BLAS;FRIGOLA-CONSTANSA, JORDI 发明人 MERCE-VIDAL, RAMON;ANDALUZ-MATERO, BLAS;FRIGOLA-CONSTANSA, JORDI
分类号 C07D231/12;A61K31/381;A61K31/415;A61P11/00;A61P11/02;A61P11/06;A61P11/08;A61P11/14;A61P37/08;(IPC1-7):A61K31/415 主分类号 C07D231/12
代理机构 代理人
主权项
地址