发明名称 |
AZOLYLCARBYNOL DERIVATIVES OF ARYL (OR HETEROARYL) FOR THE TREATMENT OF RESPIRATORY DISEASES |
摘要 |
The invention relates to azolylcarbynol derivatives of aryl (or heteroaryl) of general formula (I), wherein Ar represents an optionally substituted phenyl or thyenyl radical; R1 represents a hydrogen atom or an inferior alkyl group; R2 represents a dialkylaminoalkyl or azaheterocyclilalkyl radical and Het represents a non-substituted azole or an azole optionally substituted by one or two substituents, and their physiologically acceptable salts. Said derivatives are useful as medicaments en human and/or veterinary therapy for the treatment of respiratory diseases, more particularly for the treatment of coughing, bronchitis, chronic obstructive lung diseases, allergic rhinitis and asthma.
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申请公布号 |
WO02080908(A1) |
申请公布日期 |
2002.10.17 |
申请号 |
WO2002ES00136 |
申请日期 |
2002.03.21 |
申请人 |
LABORATORIOS DEL DR. ESTEVE, S.A.;MERCE-VIDAL, RAMON;ANDALUZ-MATERO, BLAS;FRIGOLA-CONSTANSA, JORDI |
发明人 |
MERCE-VIDAL, RAMON;ANDALUZ-MATERO, BLAS;FRIGOLA-CONSTANSA, JORDI |
分类号 |
C07D231/12;A61K31/381;A61K31/415;A61P11/00;A61P11/02;A61P11/06;A61P11/08;A61P11/14;A61P37/08;(IPC1-7):A61K31/415 |
主分类号 |
C07D231/12 |
代理机构 |
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地址 |
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