| 摘要 |
A process for the preparation of neuraminidase inhibitors having structural formula (28) or therapeutically acceptable salts thereof, in which R1 is alkyl, cycloalkyl, cycloalkylalkyl, or arylalkyl; R2 is alkyl, cycloalkyl, cycloalkylalkyl, or arylalkyl; R4 is alkyl, cycloalkyalkyl, or aryl-(C2-C4-alkyl); R10 is methyl, ethyl, iso-propyl, or vinyl; and R12 is hydrogen or alkyl and intermediates useful for the process are disclosed.
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| 申请人 |
ABBOTT LABORATORIES |
发明人 |
WITTENBERGER, STEVEN, J.;BHAGAVATULA, LAKSHMI;DEGOEY, DAVID, A.;DEMATTEI, JOHN;HILL, DAVID, R.;MCLAUGHLIN, MAUREEN, A.;GUPTA, ASHOK, K.;MANNA, SUKUMAR;NICHOLS, PAUL, J.;RAMIYA, PREMCHANDRAN, H.;TIAN, ZHENPING;RASMUSSEN, MICHAEL, W. |
