发明名称 |
Method for determining three-dimensional protein structure from primary protein sequence |
摘要 |
A preferred embodiment of the invention is a method for determining a preferred sequence alignment between a query sequence and one or more template sequences comprising the steps of: 1) aligning at least two reference sequences to determine one or more BRIDGE/BULGE gaps; 2) determining an alignment score between each potential alignment of the query sequence and each template sequence based on whether or not a given sequence alignment between the query sequence and each template sequence creates a BRIDGE/BULGE gap and 3) determining a preferred sequence alignment based on the alignment scores of the query sequence with each template sequence.
|
申请公布号 |
US2002150906(A1) |
申请公布日期 |
2002.10.17 |
申请号 |
US20010905176 |
申请日期 |
2001.07.12 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
DEBE DEREK A. |
分类号 |
G01N33/48;C07K14/00;G01N33/15;G01N33/68;G06F17/15;G06F17/30;G06F19/16;G06F19/22;(IPC1-7):C12Q1/68;G06F19/00;G01N33/50 |
主分类号 |
G01N33/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|