This invention describes gene targets for the development of therapeutics to treat drug addiction. Animal models of drug craving and relapse have been developed and used to find gene expression changes in key brain regions implicated in cocaine addiction. The genes whose expression levels are altered serve as pharmacological targets with the purpose of preventing or inhibiting cocaine craving and relapse in human cocaine addicts.
申请公布号
WO02080758(A2)
申请公布日期
2002.10.17
申请号
WO2002US11094
申请日期
2002.04.04
申请人
IRM LLC;WALKER, JOHN, R.;SELF, DAVID, W.;FRANTZ, KYLE, J.