| 发明名称 |
Inhibition of membrane-associated viral replication |
| 摘要 |
Methods for inhibiting morphogenesis of host cell membrane-budding viruses and infections caused thereby using compounds that inhibit host cell glucosidase or glucosyltransferase enzymes. Methods for treating lipid storage diseases using compounds that inhibit glucosyl transferance enzymes.
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| 申请公布号 |
US6465487(B1) |
申请公布日期 |
2002.10.15 |
| 申请号 |
US19980209033 |
申请日期 |
1998.12.10 |
| 申请人 |
SYNERGY PHARMACEUTICALS, INC.;THOMAS JEFFERSON UNIVERSITY;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD |
发明人 |
BLOCK TIMOTHY M.;DWEK RAYMOND A.;BLUMBERG BARUCH S.;MEHTA ANAND;PLATT FRANCES;BUTTERS TERRY D.;ZITZMANN NICOLE |
| 分类号 |
C07D211/46;A61K31/00;A61K31/445;A61K45/00;A61P3/06;A61P31/12;A61P35/00;A61P43/00;(IPC1-7):A61K31/445 |
主分类号 |
C07D211/46 |
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