Gamma-alpha-alkyl-glutamyl and aspartyl-cysteinyl-glycine-and intermed - iate n-carbobenzoxy alpha-alkyl-glutamic and aspartic acid anhydrides

摘要

(1) gamma-(alpha-Alkyl-glutamyl)-cysteinyl-glycine (Ia) (2) gamma-(alpha-Alkyl-aspartyl)-cysteinyl-glycine (Ib) (3) N-Carbobenzoxy alpha-alkyl glutamic and aspartic acid anhydrides (II a and b) (Ia and b) are antibiotics, anti-diabetics-anthelmintics, anti-viral agents and herbicides. The compds. antagonise glutathione and its analogues. (IIa and b) are intermediates in the prepn. of (Ia and b). Compds. (I) and (II) where "alkyl" = Me.