| 摘要 |
<p>The present invention relates to a novel one step process which involves the reaction of a suitably substituted N-alkyl-diacylhydrazine with a carbonyl equivalent such as phosgene or p-nitrophenylchloroformate or a thioocarbonyl equivalent such as thiophosgene to afford 2,4-disubstituted-1,3,4-oxadiazoline-5-thione and 5-one compounds. Such 2,4-disubstituted-1,3,4-oxadiazoline-5-thione and 5-one compounds are reported to show a broad spectrum of biological activities.</p> |
