MICROARRAY GENE EXPRESSION PROFILING IN CLEAR CELL RENAL CELL CARCINOMA: PROGNOSIS AND DRUG TARGET IDENTIFICATION

摘要

A nucleic acid probe or a novel set of such probes in a microarray is provided. The probe or probe set is useful in the prognosis of patients with clear cell renal cell carcinoma (CC-RCC), wherein aggressive and non-agressive CC-RCC tumor types are characterized by differential expression profiles of genes that hybridize with one or more of these probes. Microarrays and kits for carrying out expression profiling of tumor and normal tissue and methods of using them are disclosed.