COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF CANCER

摘要

Compositions and methods for the therapy and diagnosis of cancer, particularly cancers expressing either C-T or C-P antigens, are disclosed. Illustrative compositions comprise one or more tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly cancers expressing either C-T or C-P antigens.