发明名称 |
ASSAY METHOD, PEPTIDES AND REAGENT KITS FOR TESTING MRP-SPECIFIC INHIBITORS |
摘要 |
The invention relates to a method for testing L0-specific inhibitors of trasporter proteins of the MRP-family and for testing inhibitors specific to the predicted amphipatic helical region of the L0 region, the tested inhibitors L0 peptide, mutants thereof, polynucleotides coding the peptides, vectors and hosts cells comprising the polynucleotides and reagent kits for testing and developing the inhibitors. The invention is especially useful for combatting multidrog resistance in cancer patients and in the field of related research. |
申请公布号 |
WO0210766(A3) |
申请公布日期 |
2002.10.10 |
申请号 |
WO2001HU00085 |
申请日期 |
2001.07.30 |
申请人 |
SOLVO BIOTECHNOLOGY LTD.;BAKOS, EVA;SARKADI, BALAZS;VARADI, ANDRAS;TUSNADI, GABOR;EVERS, RAYMOND |
发明人 |
BAKOS, EVA;SARKADI, BALAZS;VARADI, ANDRAS;TUSNADI, GABOR;EVERS, RAYMOND |
分类号 |
A61K45/00;A61P35/00;A61P43/00;C07K14/47;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12Q1/02;G01N33/15;G01N33/50 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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