| 摘要 |
<p>A method for controlling the liquid volume within a fermentor using defoamer and defoamer usage information is described. The nature of this method allows for a more efficient production of desired products. Fermentor liquid volume is controlled by controlling the drop rate in proportion to the amount of defoamer used during a fermentation run. More specifically, the drop rate is proportional to the fill rate and a variable proportionality factor. The variable proportionally factor is affected by defoamer usage during a fermentation. Defoamer usage is proportional to the recent number of times the fermentor foam or fermentor liquid reached a high fermentor level, the amount of time the defoamer was dispensed during the current fermentation run and the last calculated value of the variable proportionality factor. The variable proportionality factor and the resulting drop rate are periodically updated during the fermentation run.</p> |
