发明名称 |
PREMIXED AMIODARONE PARENTERAL SOLUTION AND METHOD FOR MAKING THE SAME |
摘要 |
A premix parenteral solution for intravenous administration having amiodarone, as an active ingredient, solubilized in a solution of water for injection and about 0.4 - 12 mg/ml of a non-ionic surfactant to a concentration range of from 0.2 to 6 mg/ml is disclosed. The solution optionally may include an osmotic agent. No dilution of the solution is required before administering to a patient and the sterile packaged solution has an initial pH within the range of from about 2.9 to about 3.2, preferably about 3.1. Additionally, a method for producing an amiodarone solution suitable for intravenous administration is further disclosed. |
申请公布号 |
WO02078605(A2) |
申请公布日期 |
2002.10.10 |
申请号 |
WO2002US10094 |
申请日期 |
2002.03.28 |
申请人 |
BAXTER INTERNATIONAL INC. |
发明人 |
DOTY, MARK, J.;REBBECK, CHRISTINE, L.;KIPP, JAMES, E.;RAGHAVAN, NEERVALUR, V. |
分类号 |
C07D307/80;A61K9/00;A61K9/08;A61K31/343;A61K47/02;A61K47/10;A61K47/18;A61K47/26;A61K47/34;A61K47/36;A61P9/06 |
主分类号 |
C07D307/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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