| 摘要 |
<p>Mutated intimin polypeptides, for example at the residue equivalent to V162/252/911, T165/255/914 of Int190alpha/Int280alpha/full length intimin-alpha, or at a residues that form part of a solvent-exposed loop bordering the Tir binding site, for example residues equivalent to residue 230, 231, 232 and/ or 233 of Int280 alpha. A food product, pharmaceutical composition or vaccine comprising such an intimin polypeptide or polynucleotide.</p> |
