| 摘要 |
<p>An antibody binding to a complex of osteoclastogenesis inhibitory factor (OCIF) with a soluble OCIF-binding molecule (sOBM) (OCIF/sOBM complex) occurring in bodily fluids; a hybridoma producing this antibody; a process for producing the above antibody with the use of this hybridoma; and preventives or remedies for bone metabolic errors containing this antibody as the active ingredient. A method of diagnosing bone metabolic errors (in particular, rheumatoid arthritis) by quantifying the OCIF/sOMB complex; and a kit for diagnosing bone metabolic errors. The above-described antibody is useful in diagnosing, preventing and treating bone metabolic errors (in particular, rheumatoid arthritis) or as an analytical reagent for laboratory use.</p> |
