发明名称 |
Process for producing isocoumarins and intermediates for the same |
摘要 |
Provided is a process for producing an isocoumarin-3-yl-acetic acid derivative, characterized by reacting a homophthalic acid derivative represented by a formula: (wherein Rc, R2 and R are mainly protecting groups) with a malonic acid derivating represented by a formula: (wherein R is an organic group including a lower alkyl group; R3 is a protecting group for a carboxyl group; and X is a halogen atom or a -OM group (wherein M is alkaline metal or alkaline earth metal)). According to the above process, various isocoumarin-3-yl-acetic acid derivatives can efficiently be provided.
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申请公布号 |
US2002147350(A1) |
申请公布日期 |
2002.10.10 |
申请号 |
US20020119734 |
申请日期 |
2002.04.11 |
申请人 |
TSUCHIDA TOSHIO;NAGAI HAZUKI;NAKASHIMA TAKASHI;YOSHIDA MASASHI;KONUKI KANAME;KURODA ASAKO;ISSHIKI KUNIO;TAKEUCHI TOMIO |
发明人 |
TSUCHIDA TOSHIO;NAGAI HAZUKI;NAKASHIMA TAKASHI;YOSHIDA MASASHI;KONUKI KANAME;KURODA ASAKO;ISSHIKI KUNIO;TAKEUCHI TOMIO |
分类号 |
C07C67/343;C07C67/46;C07C69/92;C07D311/76;(IPC1-7):C07D311/02 |
主分类号 |
C07C67/343 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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