ETHYLENE GLYCOL ESTERS OF MONOHYDROBENZOPORPHYRIN DERIVATIVES AS PHOTOACTIVE AGENTS

摘要

Compounds of the formula or the metallated or labeled or conjugated form thereof wherein each R<1> is independently alkyl (1-6C); each n is independently an integer of 0-6; and R<2> is vinyl or a derivative thereof obtainable by addition or oxidation of the vinyl group; are useful in the manufacture of a photoactive compound for use in photodynamic therapy (PDT) in which the PDT is to treat tumour cells, or to modulate an immune response, to constrict or occlude vasculature or to modulate intracellular signalling.