发明名称 Stabilization of particles and reduction of sample discordance in immunoassays using casein coating of particles
摘要 It has been found that casein and salts of casein are useful as replacements for, or in addition to, BSA as materials for coating solid phases, particularly magnetic particles, used in immunoassays and other binding assays for separation of the desired analyte. By using casein, immunoassays having improved stability and fewer discordant samples have been developed. Casein used at a concentration of 0.05-4.0 grams per gram of paramagnetic particle (optimally approximately 0.78-1.2 grams of casein per gram of magnetic particle) has been found to confer this benefit.
申请公布号 US6461874(B1) 申请公布日期 2002.10.08
申请号 US20000491139 申请日期 2000.01.26
申请人 BAYER CORPORATION 发明人 NI WEI-CHAO;EUSTACE DANIEL W.;CHANG STEVE CHIN-SHEN
分类号 C12Q1/68;G01N33/53;G01N33/543;G01N33/553;G01N33/566;(IPC1-7):G01N33/553 主分类号 C12Q1/68
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