| 发明名称 |
TISSUE FACTOR PROTEIN VARIANTS |
| 摘要 |
The invention provides amino acid sequence variants of tissue factor protein. The tissue factor protein variants have a greater affinity for Factor VII/VIIa than wild-type counterparts. The invention also provides pharmaceutical compositions comprising the novel compositions as well as their use in diagnostic, therapeutic, and prophylactic methods.
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| 申请公布号 |
US2002142373(A1) |
申请公布日期 |
2002.10.03 |
| 申请号 |
US19990355000 |
申请日期 |
1999.07.14 |
| 申请人 |
GENENTECH, INC. |
发明人 |
KELLEY ROBERT F.;LEE GEOFFREY F. |
| 分类号 |
C12N15/09;A61K38/00;A61K38/36;A61P7/02;C07K14/705;C07K14/745;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;(IPC1-7):A01N37/18;C07H21/04;C12P21/06;C12N15/00;C12N15/63;C12N15/70;C12N15/74;C12N5/00;C12N5/02;C07K1/00;C07K14/00;C07K17/00 |
主分类号 |
C12N15/09 |
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