发明名称 |
Colorimetric assay system using thiopeptolide substrate for detection of membrane-type matrix metalloproteinase |
摘要 |
A calorimetric assay system to measure the expression or activity of membrane-type matrix metalloproteinases using a thiopeptolide substrate. The subject colorimetric assay system is useful in screening pharmacological agents that may have therapeutic potential in the treatment of glaucoma and the promotion of wound healing. The subject colorimetric assay system is also useful in the discovery of new therapies for cancer and conditions involving neovascularization based on modulation of extracellular matrix.
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申请公布号 |
US2002142362(A1) |
申请公布日期 |
2002.10.03 |
申请号 |
US20000576501 |
申请日期 |
2000.05.23 |
申请人 |
FLICK ROSEMARIE BETH;PFEFFER BRUCE ALAN;SHAMS NAVEED BIN KAMAL;BARTELS STEPHEN PAUL |
发明人 |
FLICK ROSEMARIE BETH;PFEFFER BRUCE ALAN;SHAMS NAVEED BIN KAMAL;BARTELS STEPHEN PAUL |
分类号 |
C12Q1/37;(IPC1-7):C12Q1/37 |
主分类号 |
C12Q1/37 |
代理机构 |
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地址 |
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