发明名称 |
CYTOTOXIC FACTORS FOR MODULATING CELL DEATH |
摘要 |
Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful i n treating conditions related to cell death. The present inventors have found that different pathogens produce different cytotoxic factor(s) having anticancer activity. The substantially pure cytotoxic factors can be used in a method of treating an infectious disease or a cancer.
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申请公布号 |
CA2436224(A1) |
申请公布日期 |
2002.10.03 |
申请号 |
CA20022436224 |
申请日期 |
2002.01.15 |
申请人 |
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS |
发明人 |
ZABORINA, OLGA;PUNJ, VASU;DAS GUPTA, TAPAS K.;CHAKRABARTY, ANANDA M. |
分类号 |
C12N15/09;A61K35/66;A61K38/00;A61K38/43;A61K38/44;A61P35/00;A61P35/02;C07K14/195;C07K14/35;C12P21/04;G01N33/50;G01N33/569;(IPC1-7):C12N1/38;C12N1/02;A61K39/04;C12Q1/04;A61K39/104;C07K1/16;C12N1/21 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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