| 发明名称 |
OLIGONUCLEOTIDE CONJUGATES |
| 摘要 |
Oligonucleotide conjugates, where an oligonucleotide is covalently attached to an aromatic system are provided. In particular embodiments, the oligonucleotide, complementary to the RNA component of telomerase, is attached to a fluorophore. The conjugates inhibit telomerase enzyme activity. |
| 申请公布号 |
CA2440322(A1) |
申请公布日期 |
2002.10.03 |
| 申请号 |
CA20022440322 |
申请日期 |
2002.03.21 |
| 申请人 |
GERON CORPORATION |
发明人 |
TOLMAN, RICHARD L.;GRYAZNOV, SERGEI;PONGRACZ, KRISZTINA;MORIN, GREGG B. |
| 分类号 |
C12N15/09;A61K31/7125;A61P35/00;A61P43/00;C07H21/00;C07H21/04;C12N9/99;(IPC1-7):C12Q1/68;C07H21/02 |
主分类号 |
C12N15/09 |
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