发明名称 |
PROANTHOCYANIDINS FOR THE TREATMENT OF AMYLOID AND ALPHA-SYNUCLEIN DISEASES |
摘要 |
A method of treating an amyloid disease, or a disease characterized by .alph a.- synuclein or NAC fibrillogenesis, in a mammalian subject. The method include s administering to the mammal a therapeutically effective amount of a various disclosed proanthocyanidins or a proanthocyanidin characterized by disclosed general formulae. A pharmaceutical composition comprising a therapeutically effective amount of a proanthocyanidin and a pharmaceutically acceptable excipient. The therapeutic amount of the proanthocyanidin is selected for efficacy in treating amyloid, .alpha.-synuclein or NAC fibrillogenesis in a mammalian subject. |
申请公布号 |
CA2441099(A1) |
申请公布日期 |
2002.10.03 |
申请号 |
CA20022441099 |
申请日期 |
2002.02.15 |
申请人 |
PROTEOTECH, INC. |
发明人 |
NGUYEN, BETH P.;SNOW, ALAN D.;CASTILLO, GERALDO M.;CHOI, PAULA Y. |
分类号 |
C07D311/62;A61K31/215;A61K31/35;A61K31/352;A61K31/353;A61K31/40;A61K36/00;A61K36/18;A61K39/385;A61P3/10;A61P25/16;A61P25/28;A61P29/00;A61P35/00;A61P35/02;C07B63/00 |
主分类号 |
C07D311/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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