发明名称 USES OF OPG LIGAND TO MODULATE IMMUNE RESPONSES
摘要 Methods of stimulating or inhibiting activity of monocytes using OPG ligand, or other agonists or antagonists, are provided. Methods of treating pathological conditions, particularly immune related conditions, using such OPG ligand, agonists or antagonists are further provided. Agonists and antagonists contemplated for use in the invention include anti-RANK receptor antibodies, anti-OPG ligand antibodies, anti-OPG receptor antibodies, RANK receptor immunoadhesins, and OPG receptor immunoadhesins.
申请公布号 CA2439678(A1) 申请公布日期 2002.10.03
申请号 CA20022439678 申请日期 2002.02.06
申请人 GENENTECH, INC. 发明人 GREWAL, IQBAL
分类号 C12N15/09;A61K38/00;A61K39/395;A61K48/00;A61P1/04;A61P3/10;A61P17/06;A61P19/00;A61P19/02;A61P29/00;A61P31/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;C07K14/705;C12N5/06;C12N5/08;(IPC1-7):A61K48/00 主分类号 C12N15/09
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