| 发明名称 |
PLASMODIUM FALCIPARUM AMA-1 PROTEIN AND USES THEREOF |
| 摘要 |
In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) AMA-1 ectodomain. The method of the present invention produces a highly purified protein which retains folding a nd disulfide bridging of the native molecule. The recombinant AMA-1 is useful a s a diagnostic reagent, for use in antibody production, and as a vaccine.</SDO AB>
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| 申请公布号 |
CA2441952(A1) |
申请公布日期 |
2002.10.03 |
| 申请号 |
CA20022441952 |
申请日期 |
2002.03.25 |
| 申请人 |
WALTER REED ARMY INSTITUTE OF RESEARCH |
发明人 |
NAIR, LALITHA P. V.;DUTTA, SHEETIJ;LANAR, DAVID E.;WARE, LISA A. |
| 分类号 |
A61K39/00;C07K14/445;C12P21/04;(IPC1-7):C12N15/30;A61K39/015;A61P33/02;C12P21/02;C07K16/20;G01N33/569 |
主分类号 |
A61K39/00 |
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