MONONUCLEOSOME AND PROCESS FOR PRODUCING THE SAME, METHOD OF ASSAYING ANTIBODY SPECIFIC TO NUCLEOSOME, METHOD OF DIAGNOSING AUTOIMMUNE DISEASE, PROCESS FOR PRODUCING NUCLEOSOME DNA, DNA PLATE, PROCESS FOR PRODUCING DNA PLATE AND METHOD OF ASSAYING ANTI-DNA ANTIBODY

摘要

It is intended to provide a process whereby a highly pure mononucleosome can be conveniently and efficiently produced. Namely, a process for producing a mononucleosome involving: the step of capturing and collecting a nucleosome contained in a sample by using an antibody specific to the nucleosome; the step of dissociating and collecting the thus captured nucleosome from the antibody; and the step of isolating and purifying a mononucleosome from the collected nucleosome depending on molecular weight.