| 摘要 |
Globular dendritic polymers having functional groups oriented on the exterior and interior surfaces of the polymer are disclosed. The inventive polymers are composed of biaryl monomer units having at least two substituents. One of the substituents orients toward the exterior surface of the globular dendritic polymer and the other substituent orients toward the interior surface of the polymer. Each substituent can be selected to have an affinity for a solvent having a particular solvent property, such as, for example, hydrophobicity, hydrophilicity, solvent polarity, pH, ionic strength. When the polymer is dissolved in a solvent having a solvent parameter for which a substituent has an affinity, that substituent orients toward the external surface of the polymer. When one substituent is hydrophilic and one substituent is hydrophobic, the polymers are facially amphiphilic. The dendritic polymers are useful for encapsulation and controlled release of pharmaceutical and agrochemical agents, catalysis, and targeted drug delivery. |
