发明名称 PROCESS FOR PRODUCING AMINE DERIVATIVES
摘要 A process for conveniently and industrially advantageously producing amine derivatives having effects of inhibiting the secretion and accumulation of amyloid .beta. protein. In compounds (I), the ether bond is selectively severed without severing the amide bond which is present in the same molecul e and tertiary amines are not converted into quaternary salts. Thus, amine derivatives (V) with good qualities having effects of inhibiting the secreti on and accumulation of amyloid .szlig. protein can be obtained at a high yield.
申请公布号 CA2404736(A1) 申请公布日期 2002.10.02
申请号 CA20012404736 申请日期 2001.04.02
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 YAMASHITA, MAKOTO;TAWADA, HIROYUKI;KATO, KANEYOSHI
分类号 A61P25/28;C07C217/74;C07C235/34;(IPC1-7):C07C217/60;C07C213/02;C07C231/12;A61K31/137 主分类号 A61P25/28
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