| 发明名称 |
Photoselection of nucleic acid ligands |
| 摘要 |
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to bFGF. Included in the invention are specific DNA ligands to bFGF identified by the photoSELEX method. Also included is a method for determining the position of a nucleic acid ligand-protein photoadduct.
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| 申请公布号 |
US6458539(B1) |
申请公布日期 |
2002.10.01 |
| 申请号 |
US20000619213 |
申请日期 |
2000.07.19 |
| 申请人 |
SOMALOGIC, INC. |
发明人 |
GOLD LARRY;SMITH JONATHAN DREW;KOCH TAD;GOLDEN MACE |
| 分类号 |
C07B61/00;C07H21/00;C12N15/10;C12Q1/68;G01N33/532;G01N33/535;G01N33/68;(IPC1-7):C12Q1/68;C12P19/34;C07H21/04;C07H21/02 |
主分类号 |
C07B61/00 |
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