Synthesis of triphenylphosphonium quinols (e.g. mitoquinol) and/or quinones (e.g. mitoquinone)

摘要

Described is a method of synthesis of a compound with a moiety or the moiety of formula (II) (and/or its quinone form) where n is an integer from 6 to 40 that comprises or includes the preparation or obtaining of a compound of formula (I) (and/or its quinol form) and the subsequent reaction of the compound of formula (I) in the presence of Ph3PHX and Ph3P, where X is a halogen atom selected from Br, I and Cl.