A pharmaceutical composition comprising cyclosporin in a lipid carrier

摘要

A pharmaceutical composition comprising a cyclosporin as an active substance in a lipid carrier, which carrier comprises membrane lipids in combination with monoglycerides and optionally non-polar lipids, which composition is characterized in being liquid at room temperature and containing 0.5-25 % cyclosporin, 10-45 % membrane lipids, 10-55 % monoglycerides and 0-45 % non-polar lipids. The composition is bioequivalent to a commercial drug containing in addition to cyclosporin and additives also toxic emulsifiers and ethanol.