AGASTACHE RUGOSA EXTRACT AND COMPOSITION CONTAINING TILIANINISOLATED AND PURIFIED FROM SAID EXTRACT HAVING ANTI-INFLAMMATORY ACTIVITY AND ANTI-ATHEROGENIC ACTIVITY

摘要

The present invention relates to a composition comprising Agastache rugosa a nd tilianin obtained by separation-purification for anti-inflammation and anti- atherosclerosis, and more particularly, to an extract of Agastache rugosa an d tilianin obtained therefrom by separation-purification which are effective i n preventing and treating not only inflammatory diseases but also atherosclerosis related to inflammatory responses and disease in circulatory system caused by atherosclerosis because they are excellent in inhibiting th e activity of complement system as a factor of inflammatory responses, the expression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecular-1 (VCAM-1), and the production of nitric oxide (NO). They can also significantly reduce the development of atherosclerosis due to the inflammatory response.