发明名称 |
NOVEL NATRIURETIC PEPTIDE RECEPTORS, INTERACTING COMPOUNDS AND METHODS OF REGULATING PROLIFERATION AND/OR SURVIVAL OF NEURONS |
摘要 |
The present invention provides methods and compositions for regulating proliferation and/or survival of neurons, to treat neuronal death and/or injury, or cancer, and to diagnose neuronal tumors, using compounds such as natriuretic peptides or PHI-related neuropeptides to interact with peptide receptor subtypes on the neurons, and provides a novel receptor on neurons that inhibits proliferation in response to natriuretic and PHI-related neuropeptides, and a novel natriuretic type-C receptor.
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申请公布号 |
WO0116295(A9) |
申请公布日期 |
2002.09.26 |
申请号 |
WO2000US24457 |
申请日期 |
2000.09.01 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;WASCHEK, JAMES, A.;LELIEVRE, VINCENT |
发明人 |
WASCHEK, JAMES, A.;LELIEVRE, VINCENT |
分类号 |
A61K38/00;A61K38/22;C07K14/72;C12N5/02;(IPC1-7):C12N5/00;A01N43/04;A61K31/70;C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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地址 |
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