摘要 |
The invention features a plug for use with a drug delivery device, wherein the plug defines an expansion control channel, which accommodates thermal expansion of a formulation in a reservoir of a drug delivery device, and an exit channel. In one embodiment, the plug comprises an inner plug member and an outer plug member, which members define an expansion control channel to facilitate release of entrapped air and to accommodate thermal expansion of formulation from the sealed drug reservoir. The plug further defines an exit channel, and may optionally further comprise a frit positioned within the flow pathway just prior to the delivery outlet, or both. |
申请人 |
DURECT CORPORATION;BROWN, JAMES, E.;CULWELL, JOHN;FILICE, JAMES, A.;GILLIS, EDWARD, M.;THEEUWES, FELIX;WICKMAN, PETER;YUM, SU, IL |
发明人 |
BROWN, JAMES, E.;CULWELL, JOHN;FILICE, JAMES, A.;GILLIS, EDWARD, M.;THEEUWES, FELIX;WICKMAN, PETER;YUM, SU, IL |