发明名称 |
Chemische Sensoren, insbesondere Biosensoren, auf Siliciumbasis |
摘要 |
PCT No. PCT/DE95/01056 Sec. 371 Date Feb. 5, 1997 Sec. 102(e) Date Feb. 5, 1997 PCT Filed Aug. 4, 1995 PCT Pub. No. WO96/05512 PCT Pub. Date Feb. 22, 1996A three-dimensional structure of porous silicon considerably improves the anchorage of sensor-active material such as, for example, enzymes, antibodies, etc., on or in the substrate surface of chemical sensors, in particular silicon-based biosensors. This structure is produced by means of suitable etching which forms pore apertures adapted to the penetrability of the sensor-active material. The pore walls advantageously receive a non-conductive boundary layer which consists of oxides of Si and/or Al or Ta or silicon nitride and are preferably 1-100 nm thick. The porous layer is advantageously between 10 nm and 100 mu m thick and the pores are preferably in the form of branched ducts whose average diameter is 1 nm-10 mu m and in particular 10-1000 nm. The sensor-active material can optionally be distributed in a glass, solid, plastics or polymer membrane. |
申请公布号 |
DE4427921(C2) |
申请公布日期 |
2002.09.26 |
申请号 |
DE19944427921 |
申请日期 |
1994.08.06 |
申请人 |
FORSCHUNGSZENTRUM JUELICH GMBH |
发明人 |
SCHOENING, MICHAEL;THUST, MARION;FROHNHOFF, STEPHAN;BERGER, MICHAEL;ARENS-FISCHER, RUEDIGER;KORDOS, PETER;LUETH, HANS |
分类号 |
G01N27/30;C12N11/00;C12Q1/00;G01N27/327;G01N27/333;G01N27/403;G01N27/414;G01N33/543;(IPC1-7):G01N27/414 |
主分类号 |
G01N27/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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