摘要 |
Antipruritics containing a nociceptin antagonist as the active ingredient. Because of having an excellent effect of preventing scratching (i.e., anti- itching and antipruritic effects), the nociceptin antagonist is usable in preventives and remedies for diseases in association with itch (for example, atopic dermatitis, urticaria), topical skin pruritus caused by insect excretions and secretions, nodular prurigo, and itch accompanying kidney dialysis, diabetes, blood diseases, liver diseases, endocrinic or metabolic errors, malignant tumor in organs, hyperthyroidism, autoimmune diseases, multiple sclerosis, nerve diseases, psychoneurosis, allergic conjunctivitis, spring catarrh, atopic keratoconjunctivitis and itch caused by over intake o f luxury foods, drugs, etc.
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