发明名称 |
USE OF A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND FOR TREATING ARTHRITIS |
摘要 |
The present invention provides a method of treatment and/or prophylaxis of arthritis in a vertebrate comprising administering to said vertebrate in need of said treatment and/or prophylaxis a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof, optionally together with a pharmaceutically acceptable carrier, diluent or excipient, wherein said compound of formula (I) is defined as: A-(L-Y)p, wherein: A comprises at least one substantially cell-membrane impermeable pendant group; L comprises any suitable linker and/or spacer group; Y comprises at least one arsenoxide or arsenoxide equivalent; p is an integer from 1 to 10; and the sum total of carbon atoms in A and L together, is greater than 6.
|
申请公布号 |
WO02074305(A1) |
申请公布日期 |
2002.09.26 |
申请号 |
WO2002AU00310 |
申请日期 |
2002.03.19 |
申请人 |
UNISEARCH LIMITED;HOGG, PHILIP, JOHN;DONOGHUE, NEIL |
发明人 |
HOGG, PHILIP, JOHN;DONOGHUE, NEIL |
分类号 |
A61K31/285;A61K47/48;A61P19/02;(IPC1-7):A61K31/285 |
主分类号 |
A61K31/285 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|